Dr Reddy's Laboratories LTD-Oncology

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• Oxaliplatin is a platinum-based cancer chemotherapy drug. These drugs are usually classified as alkylating agents, although they are not capable of actually adding alkyl groups to DNA and simply work by a similar mechanism.

• Oxaliplatin is typically administered with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin or by Medac GmbH under the trademark Oxaliplatin Medac. There are generic equivalents on the market now

• Contra Indications

Hypersensitivity.
Myelosuppression prior to starting therapy.
Peripheral sensory neuropathy.
Severely impaired renal function.
Severe infections.
Pregnancy, lactation and children.